There are already many resources that you can access across The Global Health Network to guide, teach, support and train you and your team in setting up and running high quality studies. Below you can see what can be accessed now.
Further resources will be developed specifically for the REDe community – please contact us via the contact page to suggest content you would find useful. There will also be regional meetings and workshops to identify training and development gaps. These needs will be addressed and the resources developed will be made available here and openly available for free to all.
OPEN PROTOCOLS AND DATA CAPTURE
There are two important international networks who have created research tools such as open protocols and data capture forms for Zika studies with the objective of speeding up progress and gather data that is standardised and ready, as far as possible, for sharing and amalgamating. These are ISARIC and CONSISE
The ISARIC network have worked with ISARIC, PREPARE Europe, and other partners and have developed a number of Zika Research Tools, including a set of maternal and neonatal CRFs that aim to capture core data related to ZIKV infection and a potential link to Microcephaly. All Zika-related tools, alongside information for clinicians, researchers, and other interested parties in the Zika affected countries are made available on a website on the Global Health Network that is maintained by ISARIC's Coordinating Centre: www.zikainfection.org
CONSISE has developed standardized research protocols for Influenza, MERS-CoV and Zika Virus (ZIKV)
FOR MORE INFORMATION, SUPPORT IN ADAPTING THESE PROTOCOLS FOR LOCAL USE OR SUPPORT IN THE IMPLEMENTING ANY OF THESE STUDIES, PLEASE CONTACT MARIA VAN KERKHOVE (MARIA.VAN-KERKHOVE@PASTEUR.FR)
CONSISE has drafted several standardized research protocols for influenza, MERS-CoV and Zika Virus (ZIKV). Our standardized protocols have all been developed with large numbers of technical experts, including WHO and incorporate knowledge and experience learned from conducting epidemiologic studies all over the world.
All standardized protocols have been designed to maximize the likelihood that epidemiological, clinical and exposure data and biological samples are systematically collected and shared rapidly in a format that can be easily aggregated, tabulated and analyzed across many different settings globally. We encourage any and all study centres to contribute to this effort regardless of resource availability or patient volume. Ownership of the primary data remains with the individual sites.
Consise work closely with the World Health Organization in the development of all of our protocols, and also with ISARIC (the International Severe Acute Respiratory and Emerging Infection Consortium), which focuses mainly on clinical research.
CLINICAL TRIAL TOOLS AND TEMPLATES
The Global Health Trials community (https://globalhealthtrials.tghn.org/) provides numerous research tools and templates, from data capture forms, informed consent forms, SOPs and protocol templates to career support and tools. Support from a global community of researchers is also available, as well as mentoring, career advice, and plenty of news and events.
You can access the resource page here:
https://globalhealthtrials.tghn.org/resources/ - or Spanish version here: https://globalhealthtrials.tghn.org/resources/recursos-en-espanol/
THE GLOBAL HEALTH TRAINING CENTRE - FREE TRAINING RESOURCES FOR ALL
The Global Health Training Centre (https://globalhealthtrainingcentre.tghn.org/) provides free, open-access, pragmatic eLearning courses in clinical research. These courses are high quality and very accesssible, and provide certificates to those scoring over 80% in the final quiz. Courses may be short (one module) or multi-module, and topics are covered such as introduction to informed consent, reporting adverse events, research ethics, and much more. The centre also has a scheme for recording continued professional development:https://globalhealthtrainingcentre.tghn.org/cpd/
This website provides a wealth of information, protocols and data capture tools specifically for Zika V: https://zikainfection.tghn.org/
**The Ethics Working Group on ZIKV Research & Pregnancy, an interdisciplinary group of international experts in vaccinology, maternal and child health, public health, and ethics, has developed ethics guidance for including the interests of pregnant women and their offspring in the ZIKV vaccine research agenda: “Pregnant Women & the Zika Virus Vaccine Research Agenda: Ethics Guidance on Priorities, Inclusion, and Evidence Generation.” **
This guidance provides concrete recommendations for how various actors involved in ZIKV research and development efforts can help ensure that the needs of pregnant women and their offspring are adequately included and addressed in the race toward an efficacious vaccine against ZIKV. Key audiences for the document include: global, regional and national public health agencies; ZIKV researchers and vaccine manufacturers; funders for ZIKV vaccine R&D; regulatory authorities and oversight bodies for human subjects research; and research ethics committees.
You can find more information about the project as well as the full document and executive summary on the project website: www.zikapregnancyethics.org.
Global Health Laboratories
Global Health Laboratories (https://globalhealthlaboratories.tghn.org/) provides support, information, and templates on laboratory research procedures and standards, including tools and careere support. Training materials are provides here: https://globalhealthlaboratories.tghn.org/categorised_resources/training-materials/
Intergrowth-21 provides the new Global Fetal and Newborn Growth Standards, supporting training resources and publications: ttps://intergrowth21.tghn.org/
Maternal and Child Health
This site provides support for those researching maternal and child health across the world: https://globalmotherchildresearch.tghn.org/
The Process Map
A step by step guide for setting up a new study (with links to training, tools and templates for each step)
SiteFinder is a free collaboration tool, providing an interactive database which enables research sites to exhibit their expertise. Those planning studies can share information about their planned research, and research teams can apply to take part. SiteFinder is free for all research teams https://sitefinder.tghn.org/